REAL WORLD EVENT DISCUSSIONS

new deadly human-to-human-transmissible coronavirus emerges out of China

POSTED BY: 1KIKI
UPDATED: Thursday, October 12, 2023 02:05
SHORT URL:
VIEWED: 116006
PAGE 41 of 57

Tuesday, July 28, 2020 11:00 PM

6IXSTRINGJACK


LOL

Just looked back and saw the "hater's gotta/gonna hate" thing posted several times today. Not just the one I saw toward me. It made me chuckle.


So, I'm wondering... Were you binging Taylor Swift today or did you just watch The Interview last night or something. I can't imagine you were jammin out to 3LW while doing chores around the house.

I mean, I know that phrase has long outgrown its R&B/hip hop/rap origins by now.

Just funny seeing the phrase evolve (devolve?) over 20 years to the point that Boomer Mask Karen in Commiefornia is overusing it unironically when it doesn't even make sense to use it on a defunct, outdated fan site for a show that nobody talks about anymore in 2020.




Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Tuesday, July 28, 2020 11:57 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Putting you on 'ignore'.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 12:07 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


https://www.medpagetoday.com/infectiousdisease/covid19/87790

'Immune Profiles' Shed Light on COVID-19 Disease Course

Several "immune profiles" emerged among COVID-19 patients, which appeared to lead to different disease trajectories, researchers found.

... severely ill patients had elevated levels of four immune signatures: growth factors, type 2/3 cytokines, mixed type-1/2/3 cytokines and chemokines.

Other patients showed varying degrees of these signatures. For example, those ultimately recovered with moderate disease were "enriched" in growth factors earlier in their illness.

The researchers derived a "core COVID-19 signature" common to both moderate and severe illness, defined by certain inflammatory cytokines, though patients with severe COVID-19 had an additional inflammatory cluster.

Marker profiles were initially similar in moderate and severe COVID-19, but after day 1o, markers steadily declined in moderate patients, while remaining elevated in severe patients.

Nasopharyngeal viral RNA levels were not significantly different in moderate and severe patients at the examined time points, though viral loads declined more slowly in patients sent to the ICU.

"Viral load was highly correlated with IFN-a, IFN-? and TNF-a, suggesting that viral load may drive these cytokines, and that interferons do not successfully control the virus," they wrote.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 12:46 AM

6IXSTRINGJACK


Quote:

Originally posted by 1KIKI:
Putting you on 'ignore'.



Still haven't looked up the definition of ignore yet, huh?

Here. I'll grab it for you...

Quote:

ignore verb

ig·?nore | \ ig-'n?r\

ignored; ignoring
Definition of ignore

transitive verb
1 : to refuse to take notice of
2 : to reject (a bill of indictment) as ungrounded



I'm going to assume that you mean the first definition.

Posting that you're putting me on "ignore" every time I post to you is the exact opposite of the definition of ignore.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 12:48 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.




Putting you on 'ignore'.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 1:06 AM

6IXSTRINGJACK


Okay. So you're just coming out of the closet and showing everybody that you're retarded too then.

That's cool. You're in good company here. This is certainly the place for it.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 1:06 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.




Putting you on 'ignore'.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 1:15 AM

6IXSTRINGJACK




Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 2:17 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.




Putting you on 'ignore'.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 2:25 AM

6IXSTRINGJACK




Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 4:36 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.




Putting you on 'ignore'.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 6:11 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.



Three-quarters of adults with COVID-19 have heart damage after recovery
UPI.

https://www.upi.com/Health_News/2020/07/27/Three-quarters-of-adults-wi
th-COVID-19-have-heart-damage-after-recovery/5451595856303
/






COVID-19 infections leave an impact on the heart, raising concerns about lasting damage

https://www.boston.com/news/health/2020/07/27/coronavirus-heart





Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)

Findings In this cohort study including 100 patients recently recovered from COVID-19 identified from a COVID-19 test center, cardiac magnetic resonance imaging revealed cardiac involvement in 78 patients (78%) and ongoing myocardial inflammation in 60 patients (60%), which was independent of preexisting conditions, severity and overall course of the acute illness, and the time from the original diagnosis.

Results Of the 100 included patients, 53 (53%) were male, and the median (interquartile range [IQR]) age was 49 (45-53) years. The median (IQR) time interval between COVID-19 diagnosis and CMR was 71 (64-92) days (more than two months later). Of the 100 patients recently recovered from COVID-19, 67 (67%) recovered at home, while 33 (33%) required hospitalization. At the time of CMR, high-sensitivity troponin T (hsTnT) was detectable (3 pg/mL or greater) in 71 patients recently recovered from COVID-19 (71%) and significantly elevated (13.9 pg/mL or greater) in 5 patients (5%). Compared with healthy controls and risk factor–matched controls, patients recently recovered from COVID-19 had lower left ventricular ejection fraction, higher left ventricle volumes, higher left ventricle mass, and raised native T1 and T2. A total of 78 patients recently recovered from COVID-19 (78%) had abnormal CMR findings, including raised myocardial native T1 (n?=?73), raised myocardial native T2 (n?=?60), myocardial late gadolinium enhancement (n?=?32), and pericardial enhancement (n?=?22).

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768916





Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases

Findings In this cohort study of 39 autopsy cases of patients with COVID-19, cardiac infection with SARS-CoV-2 was found to be frequent but not associated with myocarditislike influx of inflammatory cells into the myocardium.

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768914






Some patients who survive COVID-19 may suffer lasting lung damage

https://www.sciencenews.org/article/coronavirus-covid-19-some-patients
-may-suffer-lasting-lung-damage







Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study

Key Results
¦ Sixty-six of the 70 discharged patients (94%) had residual disease on final CT scans, with ground-glass opacity the most common pattern.

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768914

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 12:39 PM

6IXSTRINGJACK


Do you ever sleep anymore?

Staying up all night is not going to do your paranoia any favors.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 2:53 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.




Putting you on 'ignore'.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 3:24 PM

JEWELSTAITEFAN


Quote:

Originally posted by 1KIKI:
Three-quarters of adults with COVID-19 have heart damage after recovery
UPI.

https://www.upi.com/Health_News/2020/07/27/Three-quarters-of-adults-wi
th-COVID-19-have-heart-damage-after-recovery/5451595856303
/



COVID-19 infections leave an impact on the heart, raising concerns about lasting damage

https://www.boston.com/news/health/2020/07/27/coronavirus-heart



Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)

Findings In this cohort study including 100 patients recently recovered from COVID-19 identified from a COVID-19 test center, cardiac magnetic resonance imaging revealed cardiac involvement in 78 patients (78%) and ongoing myocardial inflammation in 60 patients (60%), which was independent of preexisting conditions, severity and overall course of the acute illness, and the time from the original diagnosis.

Results Of the 100 included patients, 53 (53%) were male, and the median (interquartile range [IQR]) age was 49 (45-53) years. The median (IQR) time interval between COVID-19 diagnosis and CMR was 71 (64-92) days (more than two months later). Of the 100 patients recently recovered from COVID-19, 67 (67%) recovered at home, while 33 (33%) required hospitalization. At the time of CMR, high-sensitivity troponin T (hsTnT) was detectable (3 pg/mL or greater) in 71 patients recently recovered from COVID-19 (71%) and significantly elevated (13.9 pg/mL or greater) in 5 patients (5%). Compared with healthy controls and risk factor–matched controls, patients recently recovered from COVID-19 had lower left ventricular ejection fraction, higher left ventricle volumes, higher left ventricle mass, and raised native T1 and T2. A total of 78 patients recently recovered from COVID-19 (78%) had abnormal CMR findings, including raised myocardial native T1 (n?=?73), raised myocardial native T2 (n?=?60), myocardial late gadolinium enhancement (n?=?32), and pericardial enhancement (n?=?22).

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768916



Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases

Findings In this cohort study of 39 autopsy cases of patients with COVID-19, cardiac infection with SARS-CoV-2 was found to be frequent but not associated with myocarditislike influx of inflammatory cells into the myocardium.

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768914



Some patients who survive COVID-19 may suffer lasting lung damage

https://www.sciencenews.org/article/coronavirus-covid-19-some-patients
-may-suffer-lasting-lung-damage




Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study

Key Results
¦ Sixty-six of the 70 discharged patients (94%) had residual disease on final CT scans, with ground-glass opacity the most common pattern.

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768914

In layman's terms, what do you think is the "damage" that is being talked about?
Muscle damage? damage to the electrical conduits (synapses, chemical balance of conductive pathway), cartigalige or ligaments, valves, synchronization of the functions?

I'm not sure what the broken glass imagery suggests - perhaps deposits in the muscle? Or damaged/dead muscle fibers?

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, July 29, 2020 3:42 PM

JEWELSTAITEFAN


I sense animosity.
Quote:

Originally posted by 1KIKI:
I also posted about a study where the HCQ-caused cardiac arrhythmias were appropriately controlled for, which did show a positive effect with HCQ. And I've pointed out - more than once - that none of the trials used zinc, which one would seem to want, in order to study the full effects.

All of this is true, and further you have been the first in RWED to post these things, diring times when RWED was largely devoid of such subject.
I have been plannning to quote them and comment, but have not found the specific original post at the same moment I've had time to comment. The above post took me a week to complete my interrupted post.
I am sincerely sorry if you feel I was attacking you. I posted that date of the original post, as a progression of showing how devoid RWED was of HCQ discussion at that time, even though the media I heard daily was constantly updating info, including almost daily input from Dr. Oz, who mentioned that the questions he was getting during these shows he was guesting on were far higher level than the questions he was accustomed to getting, including questions he had never considered before.
Quote:



But I bet you haven't even noticed those posts. Or that I've been looking at all the facts from all the 'sides'.

Incorrect assumption on both, and you are to be commended for contributing all of these mentioned.
Quote:



Because you and JACK have a narrative ...

I have done a lousy job the past 3 weeks of keeping up with posts and replies. Although I feel 6ix has made a few valid points, I don't agree with the stances of his that you focus on. I would normally be more in line with RapKnight, but I don't know what his view of all Covid concerns are.
Quote:






... because - .....

Not applicable, unless you choose to bring it up again.
Quote:



And that's how JACK can claim I'm 'afraid' and that I'm for 'full government control over everything'. And how you can fail to see my many posts that don't line up with your biases.

Well, enough about you. This is supposed to be RWE after all.



I apologize to everyone for starting a thread to keep up with facts about SARS-COV-2, and driving JACK - and JSF - over the edge with too much reality.


NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, July 30, 2020 2:58 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Quote:

Originally posted by JEWELSTAITEFAN:
In layman's terms, what do you think is the "damage" that is being talked about?
Muscle damage? damage to the electrical conduits (synapses, chemical balance of conductive pathway), cartilage or ligaments, valves, synchronization of the functions?

I'm not sure what the broken glass imagery suggests - perhaps deposits in the muscle? Or damaged/dead muscle fibers?



There seem to be several different types of damage indicated by different types of observations.

One is damage to the heart's muscle fibers (which are elongated muscle cells), such that they leak their contents into the bloodstream - troponin-T is one such indicator. It was found in 70 of 100 patients 2 months after infection, indicating the heart muscle cells were still damaged and leaking, and had failed to heal. Another is induction of heart failure - indicated by "lower left ventricular ejection fraction, higher left ventricle volumes ...". In other words, the part of the heart that pumps blood to the body doesn't squeeze very well and a lot of blood is left in the heart (lower lv ejection fraction), and it got stretched out and kind of baggy (higher lv volume). Heart failure is a generally poorly understood (or treated) progressive and fatal heart condition, where the heart progressively fails to pump blood very well. Whether or not either of these post-COVID-19 issues is recoverable or permanent is to be seen.

The other is actual virus infection of the heart muscle itself, indicated by finding reproducing virus on autopsy.

The 'ground glass' finding indicates that the small sacs where air gets exchanged - the alveoli - are uniformly filled with fluid over large lung areas. It's a uniform whitish haze over the lungs - like looking at ground glass. This is as opposed to a more limited, solid opacity, with harder edges, like you might get from a tumor.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, July 30, 2020 12:14 PM

JEWELSTAITEFAN


The ground glass image was next to a link about cardiology, so I didn't catch the lung context.

Unhealed muscle tissue/fibers. could this be lack of adequate nutrient supply? The vomit/diarrhea side effects could influence absorption of nutrients, but one wonders of something is causing this for 2 months.

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, July 30, 2020 7:21 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


There have been, still are, and will be, many, MANY trials of CQ/ HCQ in many countries and also conducted by international bodies.


This link to a database - using COVID-19 as the broadest possible search terms across the globe - came up with 2,834 listed studies of all kinds on COVID-19. These are the ones that have reached some kind of end that involve various forms of chloroquine.

Of the ones that were concluded, and that have published results, all cite either lack of benefit, or high-mortality side effects.

https://clinicaltrials.gov/ct2/show/study/NCT04343768?cond=COVID-19&am
p;draw=4&rank=126

Shahid Beheshti University of Medical Sciences
Completed
no results published

https://clinicaltrials.gov/ct2/show/study/NCT04491994?cond=COVID-19&am
p;draw=13&rank=1076

UNICEF
Completed
no results published

https://clinicaltrials.gov/ct2/show/NCT04261517?cond=COVID-19&draw
=13&rank=1042

Shanghai Public Health Clinical Center
Completed / A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19 http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2020.03.03
no difference from control

https://clinicaltrials.gov/ct2/show/NCT04341870?cond=COVID-19&draw
=13&rank=1028

Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO (CORIMUNO-VIRO)
Assistance Publique - Hôpitaux de Paris
Suspended (DSMB recommendation (futility))

https://clinicaltrials.gov/ct2/show/NCT04348474?cond=COVID-19&draw
=12&rank=918

Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19
Azidus Brasil
Suspended (Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study.)

https://clinicaltrials.gov/ct2/show/NCT04329572?cond=COVID-19&draw
=7&rank=418

Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Hospitalized Patients With Moderate to Severe COVID-19
Azidus Brasil
Suspended (Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study.)

https://clinicaltrials.gov/ct2/show/NCT04347512?cond=COVID-19&draw
=10&rank=762

EVALUATION OF THE EFFICACY OF THE HYDROXYCHLOROQUINE-AZITHROMYCIN COMBINATION IN THE IN THE PREVENTION OF COVID-19 RELATED SDRA (TEACHCOVID)
Withdrawn (In view of the notices concerning hydroxychloroquine issued by the regulatory authorities, we withdraw the protocol)

https://clinicaltrials.gov/ct2/show/NCT04358068?cond=COVID-19&draw
=9&rank=650

Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19
National Institute of Allergy and Infectious Diseases (NIAID) / Teva Pharmaceuticals Industries LTD
completed
No results published

https://clinicaltrials.gov/ct2/show/NCT04363203?cond=COVID-19&draw
=9&rank=623

VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL) (VA-REACH)
Salomeh Keyhani MD / San Francisco VA Health Care System
Suspended (concerns related to study drug)

https://clinicaltrials.gov/ct2/show/NCT04371926?cond=COVID-19&draw
=6&rank=391

Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk (PREVENT)
Texas Cardiac Arrhythmia Research Foundation
Withdrawn (Concerned about the adverse effects of HCQ)

https://clinicaltrials.gov/ct2/show/NCT04331834?cond=COVID-19&draw
=6&rank=390

Pre-Exposure Prophylaxis With Hydroxychloroquine for High-Risk Healthcare Workers During the COVID-19 Pandemic (PrEP_COVID)
Barcelona Institute for Global Health
Suspended (The study has been suspended until a new epidemic curve occurs.)

https://clinicaltrials.gov/ct2/show/NCT04323631?cond=COVID-19&draw
=6&rank=388

Hydroxychloroquine for the Treatment of Patients With Mild to Moderate COVID-19 to Prevent Progression to Severe Infection or Death
Rambam Health Care Campus (Israel)
Withdrawn (Trial not started due to accumulating evidence against HCQ for COVID)

https://clinicaltrials.gov/ct2/show/NCT04362332?cond=COVID-19&draw
=6&rank=386

Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients Admitted With Moderate to Severe COVID-19 (ARCHAIC)
UMC Utrecht / ZonMw: The Netherlands Organisation for Health Research and Development
Terminated (Currently, almost no patients admitted to Dutch hospitals. If any effect of HCQ is to be expected we need more than 1000 inclusions)

https://clinicaltrials.gov/ct2/show/NCT04307693?cond=COVID-19&draw
=6&rank=374

Comparison of Lopinavir/Ritonavir or Hydroxychloroquine in Patients With Mild Coronavirus Disease (COVID-19)
Sung-Han Kim, Asan Medical Center (Korea)
Terminated (Terminated early because no patients were further enrolled since mid-Apr 2020.)

https://clinicaltrials.gov/ct2/show/NCT04369742?cond=COVID-19&draw
=5&rank=207

Treating COVID-19 With Hydroxychloroquine (TEACH)
NYU Langone Health
Suspended (Investigator decision)

https://clinicaltrials.gov/ct2/show/NCT04329611?cond=COVID-19&draw
=32&rank=74

ALBERTA HOPE COVID-19 for the Prevention of Severe COVID19 Disease
Dr. Michael Hill / Alberta Health Services ' et al
Suspended (Enrolment was suspended on 22may2020, after Mehra et al (Lancet 2020) suggested excess toxicity of HCQ.)

https://clinicaltrials.gov/ct2/show/NCT04308668?cond=COVID-19&draw
=31&rank=2812

Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2 (COVID-19 PEP)
University of Minnesota
Completed / A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19 https://pubmed.ncbi.nlm.nih.gov/32492293/
After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid-19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure.
also https://pubmed.ncbi.nlm.nih.gov/32383125/

https://clinicaltrials.gov/ct2/show/NCT04341727?cond=COVID-19&draw
=30&rank=2720

Hydroxychloroquine,Hydroxychloroquine,Azithromycin in the Treatment of SARS CoV-2 Infection (WU352)
Washington University School of Medicine
Suspended (DSMB recommended study suspension slow accrual)

https://clinicaltrials.gov/ct2/show/NCT04323527?cond=COVID-19&draw
=29&rank=2686

Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2 (CloroCOVID19)
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (Brazil) / Marcus Vinícius Guimarães de Lacerda / et al
Completed / Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/32339248/
The preliminary findings of this study suggest that the higher CQ dosage should not be recommended for critically ill patients with COVID-19 because of its potential safety hazards, especially when taken concurrently with azithromycin and oseltamivir.
Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/32330277/
Conclusions and relevance: The preliminary findings of this study suggest that the higher CQ dosage should not be recommended for critically ill patients with COVID-19 because of its potential safety hazards, especially when taken concurrently with azithromycin and oseltamivir.

https://clinicaltrials.gov/ct2/show/NCT04389320?cond=COVID-19&draw
=28&rank=2566

Antimalarial and Covid 19 in Rheumatoid Arthritis
Assiut University (Egypt)
Completed
no Results Posted

https://clinicaltrials.gov/ct2/show/NCT04321278?cond=COVID-19&draw
=27&rank=2476

Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus (Coalition Covid-19 Brasil II)
Hospital Israelita Albert Einstein (Brazil)
Completed / Uso de antipalúdicos en el tratamiento del COVID-19: ¿una ventana de oportunidad? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174146/
... only 12.5% ??of patients in the control group had negative side effects compared to 57.1% of the patients who received 200 mg daily of hydroxychloroquine sulfate for 10 days, and 100% of those who received the combination of hydroxychloroquine and azithromycin, the latter at a dose of 500 mg on day 1, followed by 250 mg / day the following 4 days.

https://clinicaltrials.gov/ct2/show/NCT04441424?cond=COVID-19&draw
=27&rank=2434

Convalescent Plasma Therapy on Critically-ill Novel Coronavirus (COVID-19) Patients
Alkarkh Health Directorate-Baghdad
Completed / Title: The therapeuticpotential of Convalescent plasma therapy on treating critically-ill COVID-19 patients residing in respiratory care units in hospitals inBaghdad, Iraq https://clinicaltrials.gov/ProvidedDocs/24/NCT04441424/Prot_SAP_000.pd
f

no mention of any type of chloroquine was made in the text

https://clinicaltrials.gov/ct2/show/NCT04333654?cond=COVID-19&draw
=26&rank=2324

Hydroxychloroquine in Outpatient Adults With COVID-19
Sanofi
Terminated (Rate of enrollment too slow to allow completion in a reasonable timeframe)

https://clinicaltrials.gov/ct2/show/NCT04345861?cond=COVID-19&draw
=24&rank=2181

Hydroxychloroquine Plus Azithromycin Versus Hydroxychloroquine for COVID-19 Pneumonia (COVIDOC Trial) (COVIDOC)
University Hospital, Montpellier (France)
Terminated (halted prematurely.)

https://clinicaltrials.gov/ct2/show/NCT04342650?cond=COVID-19&draw
=24&rank=2156

Chloroquine Diphosphate in the Prevention of SARS in Covid-19 Infection (CloroCOVID19II)
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (Brazil)
Completed
No Results Posted

https://clinicaltrials.gov/ct2/show/NCT04361461?cond=COVID-19&draw
=22&rank=1969

Use of Hydroxychloroquine Alone or Associated for Inpatients With SARS-CoV2 Virus (COVID-19)
Apsen Farmaceutica S.A. / Federal University of São Paulo
Withdrawn (This study was canceled before enrollment due to a decision by the Sponsor)

https://clinicaltrials.gov/ct2/show/NCT04376814?cond=COVID-19&draw
=21&rank=1893

Favipiravir Plus Hydroxychloroquine and Lopinavir/Ritonavir Plus Hydroxychloroquine in COVID-19
Baqiyatallah Medical Sciences University (Iran)
Completed
No Results Posted

https://clinicaltrials.gov/ct2/show/NCT04344379?cond=COVID-19&draw
=21&rank=1867

Prevention of SARS-CoV-2 in Hospital Workers s Exposed to the Virus (PREP-COVID)
Assistance Publique - Hôpitaux de Paris (France)
Suspended (suspension of clinical trials with hydroxychloroquine by health authorities)

https://clinicaltrials.gov/ct2/show/NCT04350281?cond=COVID-19&draw
=21&rank=1850

Double Therapy With IFN-beta 1b and Hydroxychloroquine
The University of Hong Kong (China)
Completed
No Results Posted

https://clinicaltrials.gov/ct2/show/NCT04434144?cond=COVID-19&draw
=21&rank=1804

A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh
Upazila Health & Family Planning Officer's (UHFPO) Office, Chakoria, Cox's Bazar (Bangladesh)
No Results Published

https://clinicaltrials.gov/ct2/show/NCT04334967?cond=COVID-19&draw
=20&rank=1761

Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care
Providence Health & Services
Suspended (suspected unfavorable risk/benefit assessment)

https://clinicaltrials.gov/ct2/show/NCT04475588?cond=COVID-19&draw
=19&rank=1606

Efficacy and Safety of Itolizumab in COVID-19 Complications
Biocon Limited (India)
Completed
No Results Posted

https://clinicaltrials.gov/ct2/show/NCT04354441?cond=COVID-19&draw
=18&rank=1583

Effect of Hydroxychloroquine in COVID-19 Positive Pregnant Women (HyPreC)
Sir Mortimer B. Davis - Jewish General Hospital (Canada)
Withdrawn (Not started)

https://clinicaltrials.gov/ct2/show/NCT04350450?cond=COVID-19&draw
=18&rank=1524

Hydroxychloroquine Treatment of Healthcare Workers With COVID19 Illness at Montefiore
Montefiore Medical Center
Withdrawn (PI withdrew the submission to the IRB)

https://clinicaltrials.gov/ct2/show/NCT04333914?cond=COVID-19&draw
=17&rank=1440

Prospective Study in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 Infection (IMMUNONCOVID)
Centre Leon Berard (France)
Suspended (Potential recrutment related to the epidemic context.)

https://clinicaltrials.gov/ct2/show/NCT04423991?cond=COVID-19&draw
=16&rank=1367

Identification of a Responsive Subpopulation to Hydroxychloroquine in COVID-19 Patients Using Machine Learning (IDENTIFY)
Dascena
Completed
No Results Posted

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, July 30, 2020 7:45 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Having gone through the research history - "the chloroquines" have demonstrated anti-viral activity in laboratory cell cultures (in vitro) to other viruses and coronaviruses in particular in the past, and some (though not significant enough) anti-viral activity to other viruses in humans (in vivo).

HOWEVER - there have been very few completed and published trials of "the chloroquines" that are both in humans and against SARS-CoV-2.

Of the ones I found, either the results were that there was no benefit, or that "the chloroquines" carry unsupportable cardiac risk in general use, and that that risk needs to be mitigated.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, July 30, 2020 8:07 PM

SIGNYM

I believe in solving problems, not sharing them.


Quote:

I also posted about a study where the HCQ-caused cardiac arrhythmias were appropriately controlled for, which did show a positive effect with HCQ. And I've pointed out - more than once - that none of the trials used zinc, which one would seem to want, in order to study the full effects.
I read a study - wish I could remember where- a researcher was doing lab experiments on HCQ, nothing related to Covid, and he couldn't reproduce someone else's results. THen he thought to ask for a sample of the HCQ used in the original study and had it analyzed for zinc, and it was some phenomenal percentage ... my brain wants to say 27% but I don't remember for sure.

-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, July 30, 2020 8:25 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


One would wish a real study had been done with Zn+2, and maybe starting low doses early and controlling for cardiac and G6PD risk.

But, having looked thru the database, you would not BELIEVE how many things doctors were throwing at COVID-19, either individually or in combination. It sure looked to me like in these few short months, they were scrambling for something, anything that might possibly help ... even ivermectin, the antiparasitic you give your dog for roundworm.



Now, with fewer people entering the hospitals at any one time, many trials have either been suspended or terminated, because the chances of collecting mass data from any one location like a hospital in a few weeks are getting smaller. The mass outbreak of fatalities has just splintered into too many geographically disparate ones.


OTOH, since even mild cases in young people show persistent elevated troponin-T, perhaps they could readjust their aim to early intervention in mild cases to see if they can stop that persistent cardiac effect.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Saturday, August 1, 2020 3:17 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Looking at the 91-DIVOC website, I've found remarkable consistency in the relation between new cases and new deaths. If new cases spike by a factor of 5 over 2 weeks, new deaths will spike by that same factor 21 days later over 2 weeks.

Looking at the national drop in new cases in the last 2 weeks, and looking at 1k+/day level contributors only I attribute the drop to the very large contributors Texas initially at 10.5k and Florida initially at 12k dropping by multiple k's, while the very large potential contributor California held steady at 9k.

Texas dropping from 10.5k to 8k over the last week (-2.5k)
Florida dropping from 12k to 10k over 2 weeks (-2k)
California leveling off at 9k over 3 weeks (0k)
Georgia leveling off at 3.7k over 2 weeks (0k)
Tennessee (possibly) leveling off at 2.2k over the last week (0k)
Louisiana dropping from 2.2k to 1.8 over the last week (-0.4k)
N. Carolina leveling off at 1.9k over 2 weeks (0k)
S. Carolina dropping from 1.9k to 1.6k over 2 weeks (-0.3k)
Ohio leveling off at 1.4k over 2 weeks (0k)
Nevada dropping from 1.2k to 1.0k over 2 weeks (-0.2k)
Virginia (possibly) leveling off at 1.1k over the last week


The combined effects of various large contributors either decreasing or holding steady were more than enough to overcome the rising number of cases elsewhere, for example

Missouri increasing from 0.6k to 1.6K over 3 weeks
Mississippi increasing from 0.8k to 1.4k over 2 weeks
Pennsylvania increasing from 0.8k to 0.9k over the last week
Oklahoma increasing from 0.8k to 1.1k over the last week

These states along with Minnesota, Michigan, Maryland, Kentucky, and possibly California seem to have the largest immediate upside potential.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Saturday, August 1, 2020 2:00 PM

6IXSTRINGJACK


From April 25th:

Quote:

Originally posted by 6IXSTRINGJACK:
Here's a link for you, Dummy.

https://people.com/food/world-face-multiple-famines-biblical-proportio
ns-coronavirus-crisis
/

I know you don't take stuff I post seriously without one, and I don't usually care, but since male suicides in our country are of no concern for you, here's the prelude to an insane amount of people who are going to die of hunger just so you don't get a wittle cold. Boo hoo.

Quote:


UN Leader Says the World Could Face 'Famines of Biblical Proportions' amid Coronavirus Crisis

“While dealing with a COVID-19 pandemic, we are also on the brink of a hunger pandemic,” David Beasley, the director of the UN World Food Program warned

As the world continues to battle the coronavirus pandemic, the United Nations is warning that without action, the world is at risk of numerous famines “of biblical proportions” in the near future.

He explained that famines could be seen “in about three dozen countries,” ten of which already have more than 1 million people on the verge of starvation.

“There is also a real danger that more people could potentially die from the economic impact of COVID-19 than from the virus itself,” he warned.




lol

I'm right again. Imagine that.


And yes... I did mention this the other day repeatedly, but it was ignored by both of you.

Do Right, Be Right. :)






https://apnews.com/5cbee9693c52728a3808f4e7b4965cbd



Hope it's worth it Karen. Those 10,000 kids dying every month now from starvation are on your head, and the heads of all the other Karens in your neighborhood watch troll-free Karenville.

Maybe we should start making masks edible?



Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 4:28 AM

SIGNYM

I believe in solving problems, not sharing them.


Quote:

Originally posted by 1KIKI:
Quote:

Originally posted by JEWELSTAITEFAN:
In layman's terms, what do you think is the "damage" that is being talked about?
Muscle damage? damage to the electrical conduits (synapses, chemical balance of conductive pathway), cartilage or ligaments, valves, synchronization of the functions?

I'm not sure what the broken glass imagery suggests - perhaps deposits in the muscle? Or damaged/dead muscle fibers?



There seem to be several different types of damage indicated by different types of observations.

One is damage to the heart's muscle fibers (which are elongated muscle cells), such that they leak their contents into the bloodstream - troponin-T is one such indicator. It was found in 70 of 100 patients 2 months after infection, indicating the heart muscle cells were still damaged and leaking, and had failed to heal. Another is induction of heart failure - indicated by "lower left ventricular ejection fraction, higher left ventricle volumes ...". In other words, the part of the heart that pumps blood to the body doesn't squeeze very well and a lot of blood is left in the heart (lower lv ejection fraction), and it got stretched out and kind of baggy (higher lv volume). Heart failure is a generally poorly understood (or treated) progressive and fatal heart condition, where the heart progressively fails to pump blood very well. Whether or not either of these post-COVID-19 issues is recoverable or permanent is to be seen.

The other is actual virus infection of the heart muscle itself, indicated by finding reproducing virus on autopsy.

The 'ground glass' finding indicates that the small sacs where air gets exchanged - the alveoli - are uniformly filled with fluid over large lung areas. It's a uniform whitish haze over the lungs - like looking at ground glass. This is as opposed to a more limited, solid opacity, with harder edges, like you might get from a tumor.



One thing that Chris Martenson keeps mentioning is the presence of micro emboli. If you have little clots clogging up the small vessels feeding your heart, OF COURSE you'll have heart damage. And lung and kidney and CNS damage too,

In some cases the clotting gets so bad it progresses to DIC.

-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 12:15 PM

6IXSTRINGJACK


Herman Cain was dying of stage 4 colon cancer.

Discuss.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 2:50 PM

SIGNYM

I believe in solving problems, not sharing them.


Quote:

Originally posted by 6IXSTRINGJACK:
Herman Cain was dying of stage 4 colon cancer.

Discuss.

Do Right, Be Right. :)

With you?
Not likely!


-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 3:09 PM

SIGNYM

I believe in solving problems, not sharing them.


But I will address it.

According to records, Herman Cain had been SUCCESSFULLY TREATED for stage IV colon cancer in 2006. Yes, it is possible: One of my dog-walking friends was also successfully treated for Stage IV colon cancer eight years ago, so it's clear that she won't be "dying of cancer" any time soon, and neither was Herman Cain.

When he was hospitalized it was for difficulty breathing. He tested positive for Covid-19. He was treated for breathing difficulties. The course of his stay in the hospital, like so many Covid-19 patients, was up, and down. Like so many Covid-19 patients he seemed to be doing better and then died suddenly.

He had attended a Trump rally shortly before becoming sick, and nobody was wearing masks, not even him, altho he was at high risk (elderly and history of cancer) of developing severe symptoms. But nobody can say for sure where he caught it.

End of story.



-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 6:53 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Quote:

Originally posted by SIGNYM:

One thing that Chris Martenson keeps mentioning is the presence of micro emboli. If you have little clots clogging up the small vessels feeding your heart, OF COURSE you'll have heart damage. And lung and kidney and CNS damage too,

In some cases the clotting gets so bad it progresses to DIC.

-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

Then for people who are still leaking troponin-T 2 months after recovering from coronavirus, a good test would be getting anti-clot therapy, to see if it helps.
One would wish for a study on that, too!

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 7:36 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Birx warns US is 'in a new phase' of coronavirus pandemic with more widespread cases

reported everywhere

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 7:55 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Remember Stella Emmanuel - that quack doc promoting HCQ who thinks that disease is caused by demons and devil sperm?

Yep, she's part of a small group of self-selected frauds.


https://www.medpagetoday.com/infectiousdisease/covid19/87797

No Evidence That Doctor Group in Viral Video Got Near COVID 'Front Lines'
— Who are the physicians behind America's Frontline Doctors?


NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 8:04 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


https://www.statnews.com/2020/07/14/fix-covid-19-dumpster-fire-us/

How to fix the Covid-19 dumpster fire in the U.S.

On Sunday, Florida reported more than 15,000 cases — in a single day. South Korea hasn’t registered 15,000 cases in the entire pandemic to date.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 8:07 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


https://www.medpagetoday.com/infectiousdisease/covid19/87716

Not All Cloth Masks Are Equally Protective
— Droplet study shows which are better

"From the captured video it can be observed that, for speaking, a single-layer cloth face covering reduced the droplet spread but a double-layer covering performed better ... " though "Even a single-layer face covering is better than no face covering.".

A three-ply surgical mask performed best of all for every type of respiratory emission, the group noted.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 8:15 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


https://www.medicalnewstoday.com/articles/preventing-a-pandemic-is-500
-times-cheaper-than-responding-to-one


Preventing a pandemic is 500 times cheaper than responding to one


File this under duh!

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 8:18 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


https://www.medicalnewstoday.com/articles/hopeful-covid-19-research-no
t-one-but-two-vaccines-show-promise


Hopeful COVID-19 research: Not one but two vaccines show promise

Oxford vaccine trial results ‘as good as one could expect’
Chinese vaccine ‘also worked,’ but there are caveats

IMO there are caveats to all vaccines for this virus.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 9:58 PM

6IXSTRINGJACK


Quote:

Originally posted by 1KIKI:
https://www.medicalnewstoday.com/articles/hopeful-covid-19-research-no
t-one-but-two-vaccines-show-promise


Hopeful COVID-19 research: Not one but two vaccines show promise

Oxford vaccine trial results ‘as good as one could expect’
Chinese vaccine ‘also worked,’ but there are caveats

IMO there are caveats to all vaccines for this virus.




Chinese Vaccine Caveat: Chinese vaccine won't work as designed unless the nanites can be controlled by the TicTok app on your smart phone.

US Vaccine Caveat: Nanites in the US Vaccine will work exactly as designed as long as you have Facebook on your smart phone.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Sunday, August 2, 2020 10:00 PM

6IXSTRINGJACK


Quote:

Originally posted by SIGNYM:
But I will address it.

According to records, Herman Cain had been SUCCESSFULLY TREATED for stage IV colon cancer in 2006. Yes, it is possible: One of my dog-walking friends was also successfully treated for Stage IV colon cancer eight years ago, so it's clear that she won't be "dying of cancer" any time soon, and neither was Herman Cain.

When he was hospitalized it was for difficulty breathing. He tested positive for Covid-19. He was treated for breathing difficulties. The course of his stay in the hospital, like so many Covid-19 patients, was up, and down. Like so many Covid-19 patients he seemed to be doing better and then died suddenly.

He had attended a Trump rally shortly before becoming sick, and nobody was wearing masks, not even him, altho he was at high risk (elderly and history of cancer) of developing severe symptoms. But nobody can say for sure where he caught it.

End of story.



-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK




You know who agrees with you that Herman Cain died of COVID and not stage 4 colon cancer?


Every lefty Legacy Media news outlet who lied about the Russiagate hoax.

Every. Single. One.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Monday, August 3, 2020 2:12 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Dr. Birx says coronavirus is "extraordinarily widespread" in rural areas

reported everywhere

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Monday, August 3, 2020 2:14 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


The President blasts the coordinator of the coronavirus task force after she warned the pandemic is 'extraordinarily widespread' in the US

reported everywhere

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Monday, August 3, 2020 2:30 PM

6IXSTRINGJACK


And?

Not only is this a good thing, but it's something I've been telling you for MONTHS now.


Glad you finally got somebody you can "trust" to spell out the facts for you.




You can't put the shit back in the horse. Everybody is going to get COVID.


Deal.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Monday, August 3, 2020 4:03 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.



Quote:

Texas dropping from 10.5k to 8k over the last week (-2.5k)
So I looked back in the news regarding Texas and COVID-19.

On June 26, 2020 Abbott paused Texas's reopening.

Then "Gov. Greg Abbott issued an executive order on Thursday requiring Texans to wear face coverings in public in counties with 20 or more COVID-19 cases" starting July 9, 2020.

New cases plateaued between July 17-22, 2020 and started dropping after that.

It looks like Signy was right. #WEARAMASK.
Quote:

Florida dropping from 12k to 10k over 2 weeks (-2k)
Florida is more complicated because DeSantis left it to counties and localities to create their own restrictions. So it's a patchwork of quarantines for positive-testing people, mask requirements, alcohol sales prohibitions, bar and nightclub closures, beach closures, and curfews.

Some statewide measures were taken - banning on-site alcohol sales at bars and nightclubs (June 26, 2020) followed by a governor's emergency order closing bars the same day.

It appears the patchwork of restrictions and requirements may be reducing the COVID-19 surge. However, with testing places closed in parts of Florida due to Hurricane Isaias it'll be some time before accurate tracking is restored.


https://www.nbcnews.com/news/us-news/texas-governor-pauses-state-s-reo
pening-due-spike-new-covid-n1232118

https://www.npr.org/sections/coronavirus-live-updates/2020/07/02/88690
1666/face-masks-mandatory-in-most-of-texas-starting-friday

https://www.sun-sentinel.com/coronavirus/fl-ne-coronavirus-latest-rule
s-three-counties-20200730-sd6mcbzlknh7dnc5fmzwbprllq-story.html

https://www.myrtlebeachonline.com/news/article244609277.html
https://www.news4jax.com/news/local/2020/06/19/major-florida-cities-no
w-require-use-of-face-mask-in-public-places
/
https://news.yahoo.com/broward-county-nightly-curfew-extended-18220026
5.html

https://www.foxnews.com/us/florida-bans-alcohol-sales-bars-coronavirus
-cases-rapidly-rise-young-demographics

https://www.nbcnews.com/news/us-news/texas-close-bars-limit-restaurant
-dining-due-explosion-covid-19-n1232233

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Tuesday, August 4, 2020 12:23 PM

6IXSTRINGJACK


People aren't going to abide any of this lockdown nonsense for much longer.

If you don't figure it out by next spring, we're going to see some actual justified rioting on the streets.


Meanwhile, the number of Coomph deaths so far equates to 5.5% of annual US deaths.

And that's based off of 2,813,503 deaths, which was the number before Coomph was a thing. Especially if there isn't some sort of UBI system in place at that point and we're still taking in legal and illegal immigrants while 20% of the US population is living out on the streets. (The UBI would just be postponing the riots for a while, since that would be the true beginning of the end of the American economy).


No reason really to change that 2,813,503 number though, since anybody dying in elderly homes of other things, to Herman Cain dying of stave 4 colon cancer all the way down to somebody dying from a gangrenous stubbed toe and the staph infection they got while at the hospital all ended up in the Coomph death count anyways.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Tuesday, August 4, 2020 12:55 PM

SIGNYM

I believe in solving problems, not sharing them.


Quote:

Originally posted by 1KIKI:

Quote:

Texas dropping from 10.5k to 8k over the last week (-2.5k)
So I looked back in the news regarding Texas and COVID-19.

On June 26, 2020 Abbott paused Texas's reopening.

Then "Gov. Greg Abbott issued an executive order on Thursday requiring Texans to wear face coverings in public in counties with 20 or more COVID-19 cases" starting July 9, 2020.

New cases plateaued between July 17-22, 2020 and started dropping after that.

It looks like Signy was right. #WEARAMASK.

The timeline between required mask-wearing and dropping case numbers (July 9, July 17) is about right since it take, on average, five days for symptoms to appear after exposure.


BTW, Louisianna also ordered statetwide masking in about the same timeframe (Jul 11) and is also experiencing a downturn in "new cases", so this isn't rocket science.

California, has required masking up since July 6, which was approximately 28 days ago. Shortly afterwards (sooner than would be exepcted) the "new cases" curve flattened and started to reduce slightly after shooting up exponentially for about 30 days prior to that. (source divoc-91) I believe the results would be even better if better masks were available: right now most people are wearing cloth masks (the garment industry has really stepped up and cloth masks are readily available) but the surgical mask really IS better.

Businesses (grocery stores, home improvement, optometrists, dentists, doctors, restaurants etc) are open but making adjustments. They all require masks of their employees and customers, and they spend time sanitizing commonly-touched surfaces. Since you can't eat with a mask on, restaurants are doing takeout.

There are a few scofflaws with no masks at all, or wearing mask on their chin or the "anti-mask" mask,who walk thru the store unchallenged (except by the stares and glares of other customers) but businesses that don't enforce masking are discussed on Nextdoor and avoided by a lot of people.

I think the future of this is going to be like South Korea. I caught a headline of a study that "Majority of cases transmitted in the home" and that was so at-odds with the USA experience (infections driven by mass events attended by superspreaders, most infected people tranmitting the virus to none or one person) that I had to read further. The study was done in S Korea, and since they have blocked off most mass/public-tranmission routes, OF COURSE most of the transmission would be at home.

Either more N95s need to be made available for vulnerable people, or they better come up with a successful treatments because this is going to be with us for a long time.


Altho I do take hope from what you said KIKI: since there appears to be no wild host and this is a purely human disease (well, except a few cats) it COULD be wiped out entirely, existing as only samples in vials in liquid nitrogen. We're driving so many other species to extinction, we could extinguish this too, if we wanted to.


-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Tuesday, August 4, 2020 1:43 PM

6IXSTRINGJACK


You all are messing with forces of which you zero comprehension.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Tuesday, August 4, 2020 2:25 PM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.



Quote:

Originally posted by SIGNYM:

The timeline between required mask-wearing and dropping case numbers (July 9, July 17) is about right since it take, on average, five days for symptoms to appear after exposure.


BTW, Louisianna also ordered statetwide masking in about the same timeframe (Jul 11) and is also experiencing a downturn in "new cases", so this isn't rocket science.

California, has required masking up since July 6, which was approximately 28 days ago. Shortly afterwards (sooner than would be exepcted) the "new cases" curve flattened and started to reduce slightly after shooting up exponentially for about 30 days prior to that. (source divoc-91) I believe the results would be even better if better masks were available: right now most people are wearing cloth masks (the garment industry has really stepped up and cloth masks are readily available) but the surgical mask really IS better.

Businesses (grocery stores, home improvement, optometrists, dentists, doctors, restaurants etc) are open but making adjustments. They all require masks of their employees and customers, and they spend time sanitizing commonly-touched surfaces. Since you can't eat with a mask on, restaurants are doing takeout.

There are a few scofflaws with no masks at all, or wearing mask on their chin or the "anti-mask" mask,who walk thru the store unchallenged (except by the stares and glares of other customers) but businesses that don't enforce masking are discussed on Nextdoor and avoided by a lot of people.

I think the future of this is going to be like South Korea. I caught a headline of a study that "Majority of cases transmitted in the home" and that was so at-odds with the USA experience (infections driven by mass events attended by superspreaders, most infected people tranmitting the virus to none or one person) that I had to read further. The study was done in S Korea, and since they have blocked off most mass/public-tranmission routes, OF COURSE most of the transmission would be at home.

Either more N95s need to be made available for vulnerable people, or they better come up with a successful treatments because this is going to be with us for a long time.


Altho I do take hope from what you said KIKI: since there appears to be no wild host and this is a purely human disease (well, except a few cats) it COULD be wiped out entirely, existing as only samples in vials in liquid nitrogen. We're driving so many other species to extinction, we could extinguish this too, if we wanted to.


-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

One thing I was curious about was new case rate v new death rate and the link is invariant at ~21-24 days on. If 'new cases' goes up by a factor of 5 over 3 weeks, 'new deaths' will go up by a factor of 5 over 3 weeks, after a 21-24 day delay. We should see a decreasing new death rate following the decrease in the new case rate.

So now the graphs are completely visually explicable to me and I know how to read them and what to look for.

My next sally was to look at the reason why new cases are going down nationally, and it's not that it's 'just happening just because'. It's because of policies that were enacted in high-numbers states that are beating COVID-19 back - and the most crucial policy appears to be masking. (like this: "Houston Mayor Orders $250 Fines For People Who Refuse To Wear Masks")

I'm looking at something else, but I'm waiting for new numbers to come in, since there's no clear trend yet.

NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, August 5, 2020 10:45 PM

SIGNYM

I believe in solving problems, not sharing them.



So, let me clarify: Martenson still advocates masking and handwashing, but what he's saying is that if you implement strict lockdown measures, all you're doing is delaying the "first wave". I've been wondering about that myself: all nations, whether they lockdown or "let 'er rip" -or something in-between- seem to have some inherent number of people who're going to die, it's only a question of "when".

Well, I thought the point of all of this WAS to "flatten the curve" to not overwhelm the medical system. NOT to eradicate the virus or reduce the overall #cases. If that was what Martenson was hoping for, there was a little bit of goalpost-moving going on there!. If flattening the curve was the point then California has done an excellent job of flattening the curve, because it seems to be progressing thru its "first peak" rather slowly.

But he has some interesting data from Sweden, starting at 24:17 which shows Sweden having a "first peak" of deaths and a "second peak" of cases without attendant deaths.

I wonder how much of these shape of the "cases" curve is constricted by early limitations in testing. Since Sweden has had a "let 'er rip" philosophy from the beginning, why wouldn't the "cases" curve just steadily progress upwards instead of itself showing a dip? I think I would like to see an attendant "positivity" line along with the "cases" line to help me understand how much of the cases they were actually detecting along various points of the curve. Also, when facing skyrocketing death rates, the Swedish people may have taken it upon themselves to take precautions. Also, I wonder if the "first wave" (of deaths) was from the first strain of the virus, and the "second wave" (of cases) was from the more infectious mutation. I don't know the answer to that one, but I'd sure like to know!

So his video seems to be more of a caution against further lockdowns, but relying on masking and handwashing.

I think I started recommending masking up instead of lockdowns about three weeks into the USA epidemic. It seems to intrude less on people's liberties than other measures like lockdowns or "immunity passports" or mandated vaccination or microchipping people and have a lot lower impact on the economy.



Also, he makes a point of talking (again) about the long-term heart, lung, and kidney damage that even "recovered" people experience.

-----------
Pity would be no more,
If we did not MAKE men poor - William Blake

#WEARAMASK

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Wednesday, August 5, 2020 11:51 PM

6IXSTRINGJACK


At the end of the day though, masking shouldn't be mandated either.

Do Right, Be Right. :)

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, August 6, 2020 10:41 AM

1KIKI

Goodbye, kind world (George Monbiot) - In common with all those generations which have contemplated catastrophe, we appear to be incapable of understanding what confronts us.


Quote:

So, let me clarify: Martenson still advocates masking and handwashing, but what he's saying is that if you implement strict lockdown measures, all you're doing is delaying the "first wave". I've been wondering about that myself: all nations, whether they lockdown or "let 'er rip" -or something in-between- seem to have some inherent number of people who're going to die, it's only a question of "when".
I don't think that's true, though I am looking into a variation of that idea.

Why don't I think so ...

First of all, you have to define your 'population'. Are we talking about NYC and surrounding regions? Tuscaloosa? The entire US? Mali? The planet? Each of these has a distinctive mix of genetics, ages, past infections and vaccines, and current health. As observed, all of these have some relevance to getting infected and final outcome.

But supposing you define your population, how do you then figure out what the population maximum death rate is v how many are naturally protected? To do that you'd have to expose everyone ... and that's another hurdle. What dose does one select? "The dose makes the disease." And you'd have to expose them all at once. That's another hurdle, because you don't want variations in transmission due to say physical or social isolation causing some populations to naturally create protective sub-environments. And then you'd have to sit back and merely observe. How many get infected? How many die?

But the real world isn't like those circumstances at all. And the pandemic is affected by so many incidental and completely unavoidable things.

At best you might be able to observe a maximum in a place that either doesn't want to address the pandemic by policy, or simply can't due to poverty.

That lets out Sweden, btw. Despite being an outlier in European response, it's not true that it did **nothing**. (And btw Sweden's 'new cases' number seems to be going up - again.) And it lets out Mexico and Brazil, because even those recalcitrant countries were eventually forced into doing something at some level to stem the tide. Many Brazilian states and cities took action irrespective of Bolsonaro. At present Brazil stands at 14K cases/1M and 450 deaths/ 1M. But then Brazil has a severe lack of testing, so those numbers are for sure too low.

Chile is the world leader at 19,100cases/M (19%) and still climbing. The US is next at 14,700, Peru at 14,000 and Brazil at 13,500 (where the numbers stopped, as Brazil erased all its past and current COVID-19 data off its websites https://www.reuters.com/article/us-health-coronavirus-brazil-idUSKBN23
D0PW
), all still climbing as well. There doesn't seem to be any 'topping out' of cases going on in the global leaders.

In terms of cases the current highest rates is 19% of the population with no limit in sight. So ~20% does NOT seem to be the natural infection rate limit for COVID-19.

In terms of deaths/1M Belgium leads the world at 855/1M appearing to approach an asymptote. But Belgium is doing a lot to address COVID-19, so this may not be a 'natural' limit, simply a result of policy. The UK is next with the same caveats. Then comes Peru at 630/1M, which is still climbing. Where it'll top off is anybody's guess. Spain, Italy, and Sweden are next, all in varying stages of flattening out. (On this list of death the US is 8th in the world but still climbing with no leveling off visible.)

In terms of deaths/1M I wasn't able to find a maximum that was unfettered by policy.


Anyway, COVID-19 doesn't seem to have a natural limit that's been reached.




NOTIFY: N   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, August 6, 2020 1:06 PM

JEWELSTAITEFAN


I've been wondering about this:

In each State, what has been the worst County? As measured by cases per 100,000 population.

No need to go chase the info right away, but if noted when perusing other data, I think that would be interesting.

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

Thursday, August 6, 2020 3:19 PM

JEWELSTAITEFAN

NOTIFY: Y   |  REPLY  |  REPLY WITH QUOTE  |  TOP  |  HOME  

YOUR OPTIONS

NEW POSTS TODAY

USERPOST DATE

OTHER TOPICS

DISCUSSIONS
Russia Invades Ukraine. Again
Fri, April 19, 2024 06:48 - 6264 posts
Elections; 2024
Fri, April 19, 2024 06:40 - 2273 posts
This is what baseball bats are for, not to mention you're the one in a car...
Thu, April 18, 2024 23:38 - 1 posts
I'm surprised there's not an inflation thread yet
Thu, April 18, 2024 23:20 - 742 posts
FACTS
Thu, April 18, 2024 19:48 - 548 posts
Biden's a winner, Trumps a loser. Hey Jack, I Was Right
Thu, April 18, 2024 18:38 - 148 posts
QAnons' representatives here
Thu, April 18, 2024 17:58 - 777 posts
In the garden, and RAIN!!! (2)
Thu, April 18, 2024 16:51 - 3530 posts
Why does THUGR shit up the board by bumping his pointless threads?
Thu, April 18, 2024 12:38 - 9 posts
human actions, global climate change, global human solutions
Thu, April 18, 2024 10:21 - 834 posts
Russian losses in Ukraine
Wed, April 17, 2024 23:58 - 1005 posts
Sentencing Thread
Wed, April 17, 2024 22:02 - 364 posts

FFF.NET SOCIAL